Cargando…
Cell and tissue type independent age-associated DNA methylation changes are not rare but common
Age-associated DNA methylation changes have been widely reported across many different tissue and cell types. Epigenetic ‘clocks’ that can predict chronological age with a surprisingly high degree of accuracy appear to do so independently of tissue and cell-type, suggesting that a component of epige...
Autores principales: | Zhu, Tianyu, Zheng, Shijie C, Paul, Dirk S., Horvath, Steve, Teschendorff, Andrew E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821/ https://www.ncbi.nlm.nih.gov/pubmed/30482885 http://dx.doi.org/10.18632/aging.101666 |
Ejemplares similares
-
Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer
por: Chen, Yuting, et al.
Publicado: (2016) -
DNA methylation age of human tissues and cell types
por: Horvath, Steve
Publicado: (2013) -
Erratum to: DNA methylation age of human tissues and cell types
por: Horvath, Steve
Publicado: (2015) -
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
por: You, Chenglong, et al.
Publicado: (2020) -
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution
por: Zhu, Tianyu, et al.
Publicado: (2022)