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Glucose negatively affects Nrf2/SKN-1-mediated innate immunity in C. elegans
High glucose levels negatively affect immune response. However, the underlying mechanisms are not well understood. Upon infection, the round worm C. elegans induces multiple gene transcription programs, including the Nrf2/SKN-1-mediated detoxification program, to activate the innate immunity. In thi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286829/ https://www.ncbi.nlm.nih.gov/pubmed/30442878 http://dx.doi.org/10.18632/aging.101610 |