Cargando…

Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging

Replication-based telomere shortening during lifetime is species- and tissue-specific, however, its impact on healthy aging is unclear. In particular, the contribution of telomere truncation to the aging process of the CNS, where replicative senescence alone fails to explain organ aging due to low t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ain, Quratul, Schmeer, Christian, Penndorf, Diane, Fischer, Mike, Bondeva, Tzvetanka, Förster, Martin, Haenold, Ronny, Witte, Otto W, Kretz, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286833/
https://www.ncbi.nlm.nih.gov/pubmed/30472697
http://dx.doi.org/10.18632/aging.101655