Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in C. elegans

Sarcopenia, the age-related decline of muscle, is a significant and growing public health burden. C. elegans, a model organism for investigating the mechanisms of ageing, also displays sarcopenia, but the underlying mechanism(s) remain elusive. Here, we use C. elegans natural scaling of lifespan in...

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Detalles Bibliográficos
Autores principales: Gaffney, Christopher J., Pollard, Amelia, Barratt, Thomas F., Constantin-Teodosiu, Dumitru, Greenhaff, Paul L., Szewczyk, Nathaniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286836/
https://www.ncbi.nlm.nih.gov/pubmed/30455409
http://dx.doi.org/10.18632/aging.101654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286836/
https://www.ncbi.nlm.nih.gov/pubmed/30455409
http://dx.doi.org/10.18632/aging.101654

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