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Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in C. elegans

Sarcopenia, the age-related decline of muscle, is a significant and growing public health burden. C. elegans, a model organism for investigating the mechanisms of ageing, also displays sarcopenia, but the underlying mechanism(s) remain elusive. Here, we use C. elegans natural scaling of lifespan in...

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Detalles Bibliográficos
Autores principales:	Gaffney, Christopher J., Pollard, Amelia, Barratt, Thomas F., Constantin-Teodosiu, Dumitru, Greenhaff, Paul L., Szewczyk, Nathaniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286836/ https://www.ncbi.nlm.nih.gov/pubmed/30455409 http://dx.doi.org/10.18632/aging.101654

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