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BK channel overexpression on plasma membrane of fibroblasts from Hutchinson-Gilford progeria syndrome

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder wherein symptoms resembling aspects of aging are manifested at a very early age. It is a genetic condition that occurs due to a de novo mutation in the LMNA gene encoding for the nuclear structural protein lamin A. The...

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Detalles Bibliográficos
Autores principales: Zironi, Isabella, Gavoçi, Entelë, Lattanzi, Giovanna, Virelli, Angela, Amorini, Fabrizio, Remondini, Daniel, Castellani, Gastone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286842/
https://www.ncbi.nlm.nih.gov/pubmed/30398975
http://dx.doi.org/10.18632/aging.101621