Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE(2) and PGD(2) at the early stage of Alzheimer’s Disease

Transferrin (Tf) is an important iron-binding protein postulated to play a key role in iron ion (Fe) absorption via the Tf receptor (TfR), which potentially contributes to the pathogenesis of Alzheimer’s disease (AD). However, the role of Tf in AD remains unknown. Using mouse-derived neurons and APP...

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Detalles Bibliográficos
Autores principales: Lu, Chen-Di, Ma, Ji-Kang, Luo, Zheng-Yang, Tai, Qun-Xi, Wang, Pu, Guan, Pei-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286844/
https://www.ncbi.nlm.nih.gov/pubmed/30383537
http://dx.doi.org/10.18632/aging.101615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286844/
https://www.ncbi.nlm.nih.gov/pubmed/30383537
http://dx.doi.org/10.18632/aging.101615

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