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Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster

Recent experimental studies highlighted the role of hydrogen sulfide (H(2)S) in aging and longevity. The cystathionine ß-synthase (CBS) and cystathionine γ-lyase (CSE) are the key enzymes responsible for H(2)S production. Here we investigated the geroprotective effects of CSE and CBS overexpression...

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Detalles Bibliográficos
Autores principales: Shaposhnikov, Mikhail, Proshkina, Ekaterina, Koval, Lyubov, Zemskaya, Nadezhda, Zhavoronkov, Alex, Moskalev, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286861/
https://www.ncbi.nlm.nih.gov/pubmed/30408770
http://dx.doi.org/10.18632/aging.101630