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Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

The discovery of the epigenetic regulation of transcription has provided a new source of mechanistic understanding to long lasting effects of chemicals. However, this information is still seldom exploited in a toxicological context and studies of chemical effect after washout remain rare. Here we st...

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Detalles Bibliográficos
Autores principales: Limonciel, Alice, van Breda, Simone G., Jiang, Xiaoqi, Tredwell, Gregory D., Wilmes, Anja, Aschauer, Lydia, Siskos, Alexandros P., Sachinidis, Agapios, Keun, Hector C., Kopp-Schneider, Annette, de Kok, Theo M., Kleinjans, Jos C. S., Jennings, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286959/
https://www.ncbi.nlm.nih.gov/pubmed/30559759
http://dx.doi.org/10.3389/fgene.2018.00558