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Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy

Chagas disease is caused by infection with the protozoan Trypanosoma cruzi and affects over 8 million people worldwide. In spite of a powerful innate and adaptive immune response in acute infection, the parasite evades eradication, leading to a chronic persistent infection with low parasitism. Chron...

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Detalles Bibliográficos
Autores principales: Chevillard, Christophe, Nunes, João Paulo Silva, Frade, Amanda Farage, Almeida, Rafael Ribeiro, Pandey, Ramendra Pati, Nascimento, Marilda Savóia, Kalil, Jorge, Cunha-Neto, Edecio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286977/
https://www.ncbi.nlm.nih.gov/pubmed/30559742
http://dx.doi.org/10.3389/fimmu.2018.02791