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Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Gao, Shane, Kang, Zhanrong, Zhang, Meiyan, Zhao, Xin, Zhai, Yu, Huang, Jianming, Yang, Guo-Yuan, Sun, Wanju, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286985/
https://www.ncbi.nlm.nih.gov/pubmed/30559639
http://dx.doi.org/10.3389/fnins.2018.00865