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New Features on the Expression and Trafficking of mGluR1 Splice Variants Exposed by Two Novel Mutant Mouse Lines

Metabotropic glutamate receptors (mGluRs) couple to G-proteins to modulate slow synaptic transmission via intracellular second messengers. The first cloned mGluR, mGluR1, regulates motor coordination, synaptic plasticity and synapse elimination. mGluR1 undergoes alternative splicing giving rise to f...

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Detalles Bibliográficos
Autores principales: Naito, Rika, Kassai, Hidetoshi, Sakai, Yusuke, Schönherr, Sabine, Fukaya, Masahiro, Schwarzer, Christoph, Sakagami, Hiroyuki, Nakao, Kazuki, Aiba, Atsu, Ferraguti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287019/
https://www.ncbi.nlm.nih.gov/pubmed/30559646
http://dx.doi.org/10.3389/fnmol.2018.00439