Cargando…
New Features on the Expression and Trafficking of mGluR1 Splice Variants Exposed by Two Novel Mutant Mouse Lines
Metabotropic glutamate receptors (mGluRs) couple to G-proteins to modulate slow synaptic transmission via intracellular second messengers. The first cloned mGluR, mGluR1, regulates motor coordination, synaptic plasticity and synapse elimination. mGluR1 undergoes alternative splicing giving rise to f...
Autores principales: | Naito, Rika, Kassai, Hidetoshi, Sakai, Yusuke, Schönherr, Sabine, Fukaya, Masahiro, Schwarzer, Christoph, Sakagami, Hiroyuki, Nakao, Kazuki, Aiba, Atsu, Ferraguti, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287019/ https://www.ncbi.nlm.nih.gov/pubmed/30559646 http://dx.doi.org/10.3389/fnmol.2018.00439 |
Ejemplares similares
-
mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning
por: Harbers, Maria, et al.
Publicado: (2022) -
Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells
por: Sakai, Yusuke, et al.
Publicado: (2019) -
mGluR1 in cerebellar Purkinje cells is essential for the formation but not expression of associative eyeblink memory
por: Nakao, Harumi, et al.
Publicado: (2019) -
Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs
por: Sanderson, Thomas M, et al.
Publicado: (2011) -
Group I mGluRs in Therapy and Diagnosis of Parkinson’s Disease: Focus on mGluR5 Subtype
por: Azam, Shofiul, et al.
Publicado: (2022)