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Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses

Synaptic transmission requires the presynaptic release of neurotransmitter from synaptic vesicles (SVs) onto the postsynaptic neuron. Vesicular neurotransmitter transporter proteins, which use a V-ATPase-generated proton gradient, play a crucial role in packaging neurotransmitter into SVs. Recent wo...

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Detalles Bibliográficos
Autores principales: Herman, Melissa A., Trimbuch, Thorsten, Rosenmund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287022/
https://www.ncbi.nlm.nih.gov/pubmed/30559659
http://dx.doi.org/10.3389/fnsyn.2018.00044