A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation

Nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3) inflammasome is pivotal in maintaining intestinal homeostasis and sustaining enteric immune responses in the setting of inflammatory bowel diseases. Drugs acting as NLRP3 blockers could repres...

Descripción completa

Detalles Bibliográficos
Autores principales: Pellegrini, Carolina, Fornai, Matteo, Colucci, Rocchina, Benvenuti, Laura, D’Antongiovanni, Vanessa, Natale, Gianfranco, Fulceri, Federica, Giorgis, Marta, Marini, Elisabetta, Gastaldi, Simone, Bertinaria, Massimo, Blandizzi, Corrado, Antonioli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287041/
https://www.ncbi.nlm.nih.gov/pubmed/30559669
http://dx.doi.org/10.3389/fphar.2018.01405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287041/
https://www.ncbi.nlm.nih.gov/pubmed/30559669
http://dx.doi.org/10.3389/fphar.2018.01405

Ejemplares similares