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Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice

Mu opioid receptor (MOR) activation facilitates reward processing and reduces pain, and brain networks underlying these effects are under intense investigation. Mice lacking the MOR gene (MOR KO mice) show lower drug and social reward, enhanced pain sensitivity and altered emotional responses. Our p...

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Detalles Bibliográficos
Autores principales: Nasseef, Md Taufiq, Devenyi, Gabriel A., Mechling, Anna E., Harsan, Laura-Adela, Chakravarty, M. Mallar, Kieffer, Brigitte Lina, Darcq, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287113/
https://www.ncbi.nlm.nih.gov/pubmed/30559685
http://dx.doi.org/10.3389/fpsyt.2018.00643