HCV Defective Genomes Promote Persistent Infection by Modulating the Viral Life Cycle

Defective interfering (DI) RNAs have been detected in several human viruses. HCV in-frame deletions mutants (IFDMs), missing mainly the envelope proteins, have been found in patient sera and liver tissues. IFDMs replicate independently and can be trans-packaged into infectious virions in the presenc...

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Detalles Bibliográficos
Autores principales: Karamichali, Eirini, Chihab, Hajar, Kakkanas, Athanassios, Marchio, Agnes, Karamitros, Timokratis, Pogka, Vasiliki, Varaklioti, Agoritsa, Kalliaropoulos, Antonis, Martinez-Gonzales, Beatrice, Foka, Pelagia, Koskinas, Ioannis, Mentis, Andreas, Benjelloun, Soumaya, Pineau, Pascal, Georgopoulou, Urania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287115/
https://www.ncbi.nlm.nih.gov/pubmed/30559733
http://dx.doi.org/10.3389/fmicb.2018.02942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287115/
https://www.ncbi.nlm.nih.gov/pubmed/30559733
http://dx.doi.org/10.3389/fmicb.2018.02942

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