Apoptosis Induction via ATM Phosphorylation, Cell Cycle Arrest, and ER Stress by Goniothalamin and Chemodrugs Combined Effects on Breast Cancer-Derived MDA-MB-231 Cells

Goniothalamin (GTN), a styryl-lactone, exhibits inhibitory effects on many kinds of cancer cells in vitro. The objectives of this study were to investigate the anticancer activities of GTN and molecular signaling pathways associated with cell death in human breast cancer MDA-MB-231 cell line. GTN in...

Descripción completa

Detalles Bibliográficos
Autores principales: Khaw-on, Patompong, Pompimon, Wilart, Banjerdpongchai, Ratana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287143/
https://www.ncbi.nlm.nih.gov/pubmed/30598998
http://dx.doi.org/10.1155/2018/7049053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287143/
https://www.ncbi.nlm.nih.gov/pubmed/30598998
http://dx.doi.org/10.1155/2018/7049053

Ejemplares similares