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Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

While noncanonic xanthine nucleotides XMP/dXMP play an important role in balancing and maintaining intracellular purine nucleotide pool as well as in potential mutagenesis, surprisingly, acyclic nucleoside phosphonates bearing a xanthine nucleobase have not been studied so far for their antiviral pr...

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Detalles Bibliográficos
Autores principales: Baszczyňski, Ondřej, Kaiser, Martin Maxmilian, Česnek, Michal, Břehová, Petra, Jansa, Petr, Procházková, Eliška, Dračínský, Martin, Snoeck, Robert, Andrei, Graciela, Janeba, Zlatko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287304/
https://www.ncbi.nlm.nih.gov/pubmed/30497281
http://dx.doi.org/10.1177/2040206618813050