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In silico-designed lignin peroxidase from Phanerochaete chrysosporium shows enhanced acid stability for depolymerization of lignin

BACKGROUND: The lignin peroxidase isozyme H8 from the white-rot fungus Phanerochaete chrysosporium (LiPH8) demonstrates a high redox potential and can efficiently catalyze the oxidation of veratryl alcohol, as well as the degradation of recalcitrant lignin. However, native LiPH8 is unstable under ac...

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Detalles Bibliográficos
Autores principales: Pham, Le Thanh Mai, Seo, Hogyun, Kim, Kyung-Jin, Kim, Yong Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287364/
https://www.ncbi.nlm.nih.gov/pubmed/30555531
http://dx.doi.org/10.1186/s13068-018-1324-4