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Hantavirus-Driven PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism

Viruses often subvert antiviral immune responses by taking advantage of inhibitory immune signaling. We investigated if hantaviruses use this strategy. Hantaviruses cause viral hemorrhagic fever (VHF) which is associated with strong immune activation resulting in vigorous CD8+ T cell responses. Surp...

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Detalles Bibliográficos
Autores principales: Raftery, Martin J., Abdelaziz, Mohammed O., Hofmann, Jörg, Schönrich, Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287426/
https://www.ncbi.nlm.nih.gov/pubmed/30559738
http://dx.doi.org/10.3389/fimmu.2018.02560