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Hantavirus-Driven PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism
Viruses often subvert antiviral immune responses by taking advantage of inhibitory immune signaling. We investigated if hantaviruses use this strategy. Hantaviruses cause viral hemorrhagic fever (VHF) which is associated with strong immune activation resulting in vigorous CD8+ T cell responses. Surp...
Autores principales: | Raftery, Martin J., Abdelaziz, Mohammed O., Hofmann, Jörg, Schönrich, Günther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287426/ https://www.ncbi.nlm.nih.gov/pubmed/30559738 http://dx.doi.org/10.3389/fimmu.2018.02560 |
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