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Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not altered by ivermectin treatment

Mass administration of macrocyclic lactones targets the transmission of the causative agents of lymphatic filariasis to their insect vectors by rapidly clearing microfilariae (Mf) from the circulation. It has been proposed that the anti-filarial action of these drugs may be mediated through the host...

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Detalles Bibliográficos
Autores principales: Reaves, Barbara J., Wallis, Connor, McCoy, Ciaran J., Lorenz, W. Walter, Rada, Balazs, Wolstenholme, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287470/
https://www.ncbi.nlm.nih.gov/pubmed/30279092
http://dx.doi.org/10.1016/j.ijpddr.2018.09.002