Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus

Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic drugs. The ACC-1 family of receptors are a unique group of acetylcholine-gated chloride channels present only in invertebrates, and sequence analysis suggests that...

Descripción completa

Detalles Bibliográficos
Autores principales: Habibi, Sarah A., Callanan, Micah, Forrester, Sean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628.
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287471/
https://www.ncbi.nlm.nih.gov/pubmed/30266440
http://dx.doi.org/10.1016/j.ijpddr.2018.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287471/
https://www.ncbi.nlm.nih.gov/pubmed/30266440
http://dx.doi.org/10.1016/j.ijpddr.2018.09.004

Ejemplares similares