Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor

Serotonin (5-HT) is an important regulator of numerous aspects of flatworm biology, ranging from neuromuscular function to sexual maturation and egg laying. In the parasitic blood fluke Schistosoma mansoni, 5-HT targets several G-protein coupled receptors (GPCRs), one of which has been demonstrated...

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Detalles Bibliográficos
Autores principales: Marchant, Jonathan S., Harding, Wayne W., Chan, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628.
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287472/
https://www.ncbi.nlm.nih.gov/pubmed/30297303
http://dx.doi.org/10.1016/j.ijpddr.2018.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287472/
https://www.ncbi.nlm.nih.gov/pubmed/30297303
http://dx.doi.org/10.1016/j.ijpddr.2018.09.001

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