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Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice

Plasminogen activator inhibitor 1 (PAI‐1), an essential regulator of fibrinolysis, is increasingly implicated in the pathogenesis of metabolic disorders, such as obesity and nonalcoholic fatty liver disease (NAFLD). Pharmacologic inhibition of PAI‐1 is emerging as a highly promising therapeutic stra...

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Detalles Bibliográficos
Autores principales:	Henkel, Anne S., Khan, Sadiya S., Olivares, Shantel, Miyata, Toshio, Vaughan, Douglas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287480/ https://www.ncbi.nlm.nih.gov/pubmed/30556037 http://dx.doi.org/10.1002/hep4.1259

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