Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice

Plasminogen activator inhibitor 1 (PAI‐1), an essential regulator of fibrinolysis, is increasingly implicated in the pathogenesis of metabolic disorders, such as obesity and nonalcoholic fatty liver disease (NAFLD). Pharmacologic inhibition of PAI‐1 is emerging as a highly promising therapeutic stra...

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Detalles Bibliográficos
Autores principales: Henkel, Anne S., Khan, Sadiya S., Olivares, Shantel, Miyata, Toshio, Vaughan, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287480/
https://www.ncbi.nlm.nih.gov/pubmed/30556037
http://dx.doi.org/10.1002/hep4.1259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287480/
https://www.ncbi.nlm.nih.gov/pubmed/30556037
http://dx.doi.org/10.1002/hep4.1259

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