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Role of PAI-1 in hepatic steatosis and dyslipidemia

Plasminogen activator inhibitor 1 (PAI-1) is a functional biomarker of the metabolic syndrome. Previous studies have demonstrated that PAI-1 is a mechanistic contributor to several elements of the syndrome, including obesity, hypertension and insulin resistance. Here we show that PAI-1 is also a cri...

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Detalles Bibliográficos
Autores principales: Levine, Joshua A., Oleaga, Carlota, Eren, Mesut, Amaral, Ansel P., Shang, Meng, Lux, Elizabeth, Khan, Sadiya S., Shah, Sanjiv J., Omura, Yasuhiro, Pamir, Nathalie, Hay, Joshua, Barish, Grant, Miyata, Toshio, Tavori, Hagai, Fazio, Sergio, Vaughan, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801442/
https://www.ncbi.nlm.nih.gov/pubmed/33432099
http://dx.doi.org/10.1038/s41598-020-79948-x