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Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability
Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and regulation of gene expression(1–4). The establishment and epigenetic maintenance of heterochromatin involve the recruitment of H3K9 methyltransferases to specific sites on DNA f...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287498/ https://www.ncbi.nlm.nih.gov/pubmed/30051891 http://dx.doi.org/10.1038/s41586-018-0398-2 |