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Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus

The cys-loop superfamily of ligand-gated ion channels are well recognized as important drug targets for many invertebrate specific compounds. With the rise in resistance seen worldwide to existing anthelmintics, novel drug targets must be identified so new treatments can be developed. The acetylchol...

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Detalles Bibliográficos
Autores principales: Callanan, Micah K., Habibi, Sarah A., Law, Wen Jing, Nazareth, Kristen, Komuniecki, Richard L., Forrester, Sean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287539/
https://www.ncbi.nlm.nih.gov/pubmed/30401619
http://dx.doi.org/10.1016/j.ijpddr.2018.10.010