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Salubrinal abrogates palmitate-induced leptin resistance and endoplasmic reticulum stress via nuclear factor kappa-light-chain-enhancer of activated B cell pathway in mHypoE-44 hypothalamic neurons

BACKGROUND: The prevalence of obesity is growing rapidly and has become a global problem that increases the risk for many diseases. It is influenced by many factors, including consumption of the Western-style diet, characterized as a high-fat diet. Within the central nervous system, the hypothalamus...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Jiang, Xiaohong, Qu, Meidi, Gu, Hongliu, Sha, Qi, Hua, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287548/
https://www.ncbi.nlm.nih.gov/pubmed/30584344
http://dx.doi.org/10.2147/DMSO.S179346