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Salubrinal abrogates palmitate-induced leptin resistance and endoplasmic reticulum stress via nuclear factor kappa-light-chain-enhancer of activated B cell pathway in mHypoE-44 hypothalamic neurons
BACKGROUND: The prevalence of obesity is growing rapidly and has become a global problem that increases the risk for many diseases. It is influenced by many factors, including consumption of the Western-style diet, characterized as a high-fat diet. Within the central nervous system, the hypothalamus...
Autores principales: | Zhang, Min, Jiang, Xiaohong, Qu, Meidi, Gu, Hongliu, Sha, Qi, Hua, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287548/ https://www.ncbi.nlm.nih.gov/pubmed/30584344 http://dx.doi.org/10.2147/DMSO.S179346 |
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