Cargando…

Salubrinal abrogates palmitate-induced leptin resistance and endoplasmic reticulum stress via nuclear factor kappa-light-chain-enhancer of activated B cell pathway in mHypoE-44 hypothalamic neurons

BACKGROUND: The prevalence of obesity is growing rapidly and has become a global problem that increases the risk for many diseases. It is influenced by many factors, including consumption of the Western-style diet, characterized as a high-fat diet. Within the central nervous system, the hypothalamus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Min, Jiang, Xiaohong, Qu, Meidi, Gu, Hongliu, Sha, Qi, Hua, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287548/ https://www.ncbi.nlm.nih.gov/pubmed/30584344 http://dx.doi.org/10.2147/DMSO.S179346

Ejemplares similares

Phlorotannins from Ecklonia cava Attenuates Palmitate-Induced Endoplasmic Reticulum Stress and Leptin Resistance in Hypothalamic Neurons
por: Oh, Seyeon, et al.
Publicado: (2019)

All roads go to Salubrinal: endoplasmic reticulum stress, neuroprotection and glial scar formation
por: Romero-Ramírez, Lorenzo, et al.
Publicado: (2015)

Salubrinal Alleviates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Endoplasmic Reticulum Stress Pathway
por: Rani, Shilpa, et al.
Publicado: (2017)

Glucose Alters Per2 Rhythmicity Independent of AMPK, Whereas AMPK Inhibitor Compound C Causes Profound Repression of Clock Genes and AgRP in mHypoE-37 Hypothalamic Neurons
por: Oosterman, Johanneke E., et al.
Publicado: (2016)

Salubrinal Exposes Anticancer Properties in Inflammatory Breast Cancer Cells by Manipulating the Endoplasmic Reticulum Stress Pathway
por: Alsterda, Andrew, et al.
Publicado: (2021)

Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis
por: Griffin, Haven, et al.
Publicado: (2022)

The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates
por: Park, Soyoung, et al.
Publicado: (2020)

Salubrinal Protects Against Cisplatin-Induced Cochlear Hair Cell Endoplasmic Reticulum Stress by Regulating Eukaryotic Translation Initiation Factor 2α Signalling
por: Lu, Wen, et al.
Publicado: (2022)

Fluvoxamine Attenuated Endoplasmic Reticulum Stress-Induced Leptin Resistance
por: Hosoi, Toru, et al.
Publicado: (2012)

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress
por: Preninka, Arini Isnani, et al.
Publicado: (2022)

Hypothalamic kappa opioid receptor mediates both diet‐induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress
por: Imbernon, Monica, et al.
Publicado: (2016)

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation
por: YIN, JIAJING, et al.
Publicado: (2015)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum
por: Wang, Yisu, et al.
Publicado: (2021)

The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts
por: Yang, Hsiang-Yu, et al.
Publicado: (2022)

Neuroprotection by salubrinal treatment in global cerebral ischemia
por: Anuncibay-Soto, Berta, et al.
Publicado: (2016)

Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum
por: Trentzsch, Marcus, et al.
Publicado: (2020)

Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
por: Hosoi, Toru, et al.
Publicado: (2014)

Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis
por: Hamamura, K., et al.
Publicado: (2015)

Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
por: Chen, Zhi, et al.
Publicado: (2019)

Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs
por: Luo, Ruixi, et al.
Publicado: (2021)

Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice
por: McGavigan, Anne K., et al.
Publicado: (2017)

Possible Pharmacological Approach Targeting Endoplasmic Reticulum Stress to Ameliorate Leptin Resistance in Obesity
por: Hosoi, Toru, et al.
Publicado: (2016)

Interleukin-22 Alleviated Palmitate-Induced Endoplasmic Reticulum Stress in INS-1 Cells through Activation of Autophagy
por: Hu, Minling, et al.
Publicado: (2016)

Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum
por: Kuok, Iok Teng, et al.
Publicado: (2019)

Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis
por: Yang, Lei, et al.
Publicado: (2019)

GRP75 mediates endoplasmic reticulum–mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis
por: Tiwary, Shweta, et al.
Publicado: (2021)

Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons
por: White, Acacia, et al.
Publicado: (2022)

Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
por: Yang, Leilei, et al.
Publicado: (2023)

Endoplasmic Reticulum Resident Protein 44 (ERp44) Deficiency in Mice and Zebrafish Leads to Cardiac Developmental and Functional Defects
por: Wang, Ding‐Yan, et al.
Publicado: (2014)

Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue
por: Gan, Lu, et al.
Publicado: (2017)

Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
por: Zhang, Yong, et al.
Publicado: (2011)

Metformin Attenuates Palmitate-Induced Endoplasmic Reticulum Stress, Serine Phosphorylation of IRS-1 and Apoptosis in Rat Insulinoma Cells
por: Simon-Szabó, Laura, et al.
Publicado: (2014)

Stearate‐to‐palmitate ratio modulates endoplasmic reticulum stress and cell apoptosis in non‐B non‐C hepatoma cells
por: Shibasaki, Yasushi, et al.
Publicado: (2018)

Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells
por: Chen, Zhi, et al.
Publicado: (2019)

Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum
por: Ye, Mao, et al.
Publicado: (2017)

Berberine alleviates palmitic acid-induced podocyte apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress
por: Xiang, Xing-Yang, et al.
Publicado: (2021)

Environment, Leptin Sensitivity, and Hypothalamic Plasticity
por: Mainardi, Marco, et al.
Publicado: (2013)

Distinctive Subcellular Inhibition of Cytokine-Induced Src by Salubrinal and Fluid Flow
por: Wan, Qiaoqiao, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m0gbrope55kecujjopf7g9otfs