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Müller Cell Regulated Microglial Activation and Migration in Rats With N-Methyl-N-Nitrosourea-Induced Retinal Degeneration

During the pathogenesis of retinitis pigmentosa (RP), the roles of retinal microglial cells after activation have not been fully elucidated. Herein, experimental RP was induced in Sprague Dawley rats by intraperitoneal injection of N-methyl-N-nitrosourea (MNU) at 50 mg/kg, and the effects of MNU on...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Zhang, Shanshan, Gong, Wenqing, Zhu, Guopei, Wang, Songtao, Wang, Yalin, Halim, Michael, Wang, Kaidi, Zhou, Guomin, Liu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287671/
https://www.ncbi.nlm.nih.gov/pubmed/30559643
http://dx.doi.org/10.3389/fnins.2018.00890