Characterization of zolbetuximab in pancreatic cancer models

In healthy tissue, the tight junction protein Claudin 18.2 (CLDN18.2) is present only in the gastric mucosa. Upon malignant transformation of gastric epithelial tissue, perturbations in cell polarity lead to cell surface exposure of CLDN18.2 epitopes. Moreover, CLDN18.2 is aberrantly expressed in ma...

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Detalles Bibliográficos
Autores principales: Türeci, Ӧzlem, Mitnacht-Kraus, Rita, Wöll, Stefan, Yamada, Tomohiro, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287799/
https://www.ncbi.nlm.nih.gov/pubmed/30546962
http://dx.doi.org/10.1080/2162402X.2018.1523096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287799/
https://www.ncbi.nlm.nih.gov/pubmed/30546962
http://dx.doi.org/10.1080/2162402X.2018.1523096

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