powerTCR: A model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

Sequencing of the T cell receptor (TCR) repertoire is a powerful tool for deeper study of immune response, but the unique structure of this type of data makes its meaningful quantification challenging. We introduce a new method, the Gamma-GPD spliced threshold model, to address this difficulty. This...

Descripción completa

Detalles Bibliográficos
Autores principales: Koch, Hillary, Starenki, Dmytro, Cooper, Sara J., Myers, Richard M., Li, Qunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287877/
https://www.ncbi.nlm.nih.gov/pubmed/30485278
http://dx.doi.org/10.1371/journal.pcbi.1006571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287877/
https://www.ncbi.nlm.nih.gov/pubmed/30485278
http://dx.doi.org/10.1371/journal.pcbi.1006571

Ejemplares similares