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A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy

Immune checkpoint inhibitors have shown great potential in treating solid tumors, inducing durable remission and prolonged survival time in responders. Despite their promise, a large fraction of patients remains unresponsive to these treatments highlighting the need for biomarkers that can predict p...

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Detalles Bibliográficos
Autores principales: Varn, Frederick S., Wang, Yue, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287894/
https://www.ncbi.nlm.nih.gov/pubmed/30546953
http://dx.doi.org/10.1080/2162402X.2018.1513440