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Autophagy maintains tumor growth through circulating arginine

Autophagy captures intracellular components and delivers them to lysosomes where they are degraded and recycled to sustain metabolism and to enable survival in starvation(1–5). Acute, whole-body deletion of the essential autophagy gene Atg7 in adult mice causes a systemic metabolic defect manifested...

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Detalles Bibliográficos
Autores principales: Poillet-Perez, Laura, Xie, Xiaoqi, Zhan, Le, Yang, Yang, Sharp, Daniel W., Hu, Zhixian Sherrie, Su, Xiaoyang, Maganti, Anurag, Jiang, Cherry, Lu, Wenyun, Zheng, Haiyan, Bosenberg, Marcus W., Mehnert, Janice M., Guo, Jessie Yanxiang, Lattime, Edmund, Rabinowitz, Joshua D., White, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287937/
https://www.ncbi.nlm.nih.gov/pubmed/30429607
http://dx.doi.org/10.1038/s41586-018-0697-7