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Autophagy maintains tumor growth through circulating arginine
Autophagy captures intracellular components and delivers them to lysosomes where they are degraded and recycled to sustain metabolism and to enable survival in starvation(1–5). Acute, whole-body deletion of the essential autophagy gene Atg7 in adult mice causes a systemic metabolic defect manifested...
Autores principales: | Poillet-Perez, Laura, Xie, Xiaoqi, Zhan, Le, Yang, Yang, Sharp, Daniel W., Hu, Zhixian Sherrie, Su, Xiaoyang, Maganti, Anurag, Jiang, Cherry, Lu, Wenyun, Zheng, Haiyan, Bosenberg, Marcus W., Mehnert, Janice M., Guo, Jessie Yanxiang, Lattime, Edmund, Rabinowitz, Joshua D., White, Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287937/ https://www.ncbi.nlm.nih.gov/pubmed/30429607 http://dx.doi.org/10.1038/s41586-018-0697-7 |
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