Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs in mitosis. Here, we show that two highly cons...

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Detalles Bibliográficos
Autores principales: Pellacani, Claudia, Bucciarelli, Elisabetta, Renda, Fioranna, Hayward, Daniel, Palena, Antonella, Chen, Jack, Bonaccorsi, Silvia, Wakefield, James G, Gatti, Maurizio, Somma, Maria Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287947/
https://www.ncbi.nlm.nih.gov/pubmed/30475206
http://dx.doi.org/10.7554/eLife.40325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287947/
https://www.ncbi.nlm.nih.gov/pubmed/30475206
http://dx.doi.org/10.7554/eLife.40325

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