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Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation
Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs in mitosis. Here, we show that two highly cons...
Autores principales: | Pellacani, Claudia, Bucciarelli, Elisabetta, Renda, Fioranna, Hayward, Daniel, Palena, Antonella, Chen, Jack, Bonaccorsi, Silvia, Wakefield, James G, Gatti, Maurizio, Somma, Maria Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287947/ https://www.ncbi.nlm.nih.gov/pubmed/30475206 http://dx.doi.org/10.7554/eLife.40325 |
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