Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

Schistosomiasis endangers the lives of greater than 200 million people every year and is predominantly controlled by a single class chemotherapy, praziquantel (PZQ). Development of PZQ replacement (to combat the threat of PZQ insensitivity/resistance arising) or combinatorial (to facilitate the kill...

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Detalles Bibliográficos
Autores principales: Padalino, Gilda, Ferla, Salvatore, Brancale, Andrea, Chalmers, Iain W., Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628.
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288008/
https://www.ncbi.nlm.nih.gov/pubmed/30455056
http://dx.doi.org/10.1016/j.ijpddr.2018.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288008/
https://www.ncbi.nlm.nih.gov/pubmed/30455056
http://dx.doi.org/10.1016/j.ijpddr.2018.10.005

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