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A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia

Antipsychotic (AP) drugs are used to treat psychiatric disorders but are associated with significant weight gain and metabolic disease. Increased food intake (hyperphagia) appears to be a driving force by which APs induce weight gain but the mechanisms are poorly understood. Here we report that admi...

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Detalles Bibliográficos
Autores principales: Perez-Gomez, Anabel, Carretero, Maria, Weber, Natalie, Peterka, Veronika, To, Alan, Titova, Viktoriya, Solis, Gregory, Osborn, Olivia, Petrascheck, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288085/
https://www.ncbi.nlm.nih.gov/pubmed/30532051
http://dx.doi.org/10.1038/s41467-018-07684-y