Assessment of proportional hazard assumption in aggregate data: a systematic review on statistical methodology in clinical trials using time-to-event endpoint

BACKGROUND: The evaluation of the proportional hazards (PH) assumption in survival analysis is an important issue when Hazard Ratio (HR) is chosen as summary measure. The aim is to assess the appropriateness of statistical methods based on the PH assumption in oncological trials. METHODS: We selecte...

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Detalles Bibliográficos
Autores principales: Rulli, Eliana, Ghilotti, Francesca, Biagioli, Elena, Porcu, Luca, Marabese, Mirko, D’Incalci, Maurizio, Bellocco, Rino, Torri, Valter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288087/
https://www.ncbi.nlm.nih.gov/pubmed/30420618
http://dx.doi.org/10.1038/s41416-018-0302-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288087/
https://www.ncbi.nlm.nih.gov/pubmed/30420618
http://dx.doi.org/10.1038/s41416-018-0302-8

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