Dichloroacetate and Salinomycin Exert a Synergistic Cytotoxic Effect in Colorectal Cancer Cell Lines

In the present study, we examined a hypothesis that dichloroacetate, a metabolic inhibitor, might efficiently potentiate the cytotoxic effect of salinomycin, an antibiotic ionophore, on two human colorectal cancer derived cell lines DLD-1 and HCT116. First, we performed a series of dose response exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Skeberdytė, Aistė, Sarapinienė, Ieva, Aleksander-Krasko, Jan, Stankevičius, Vaidotas, Sužiedėlis, Kęstutis, Jarmalaitė, Sonata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288092/
https://www.ncbi.nlm.nih.gov/pubmed/30531808
http://dx.doi.org/10.1038/s41598-018-35815-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288092/
https://www.ncbi.nlm.nih.gov/pubmed/30531808
http://dx.doi.org/10.1038/s41598-018-35815-4

Ejemplares similares