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Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice

Many preclinically promising therapies for diabetic kidney disease fail to provide efficacy in humans, reflecting limited quantitative translational understanding between rodent models and human disease. To quantitatively bridge interspecies differences, we adapted a mathematical model of renal func...

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Detalles Bibliográficos
Autores principales: Mahato, Hari Shankar, Ahlstrom, Christine, Jansson-Löfmark, Rasmus, Johansson, Ulrika, Helmlinger, Gabriel, Hallow, K. Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288095/
https://www.ncbi.nlm.nih.gov/pubmed/30564457
http://dx.doi.org/10.1038/s41540-018-0077-9