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Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice
Many preclinically promising therapies for diabetic kidney disease fail to provide efficacy in humans, reflecting limited quantitative translational understanding between rodent models and human disease. To quantitatively bridge interspecies differences, we adapted a mathematical model of renal func...
Autores principales: | Mahato, Hari Shankar, Ahlstrom, Christine, Jansson-Löfmark, Rasmus, Johansson, Ulrika, Helmlinger, Gabriel, Hallow, K. Melissa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288095/ https://www.ncbi.nlm.nih.gov/pubmed/30564457 http://dx.doi.org/10.1038/s41540-018-0077-9 |
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