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Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice

Limbal epithelial stem cells (LESCs) are believed to be responsible for corneal epithelial maintenance and repair after injury, but their activity has never been properly quantified in aging or wounded eyes. In this study, labelling with thymidine analogues, 5-iodo-2′-deoxyuridine (IdU), 5-chloro-2′...

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Detalles Bibliográficos
Autores principales: Sagga, Nada, Kuffová, Lucia, Vargesson, Neil, Erskine, Lynda, Collinson, J. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288239/
https://www.ncbi.nlm.nih.gov/pubmed/30439642
http://dx.doi.org/10.1016/j.scr.2018.11.001