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Therapeutic Targeting of HIV Reservoirs: How to Give T Cells a New Direction

HIV cannot be cured by current antiretroviral therapy (ART) because it persists in a transcriptionally silent form in long-lived CD4+ cells. Leading efforts to develop a functional cure have prioritized latency reversal to expose infected cells to immune surveillance, coupled with enhancement of the...

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Detalles Bibliográficos
Autores principales: Yang, Hongbing, Wallace, Zoë, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288286/
https://www.ncbi.nlm.nih.gov/pubmed/30564246
http://dx.doi.org/10.3389/fimmu.2018.02861