Cargando…
Therapeutic Targeting of HIV Reservoirs: How to Give T Cells a New Direction
HIV cannot be cured by current antiretroviral therapy (ART) because it persists in a transcriptionally silent form in long-lived CD4+ cells. Leading efforts to develop a functional cure have prioritized latency reversal to expose infected cells to immune surveillance, coupled with enhancement of the...
Autores principales: | Yang, Hongbing, Wallace, Zoë, Dorrell, Lucy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288286/ https://www.ncbi.nlm.nih.gov/pubmed/30564246 http://dx.doi.org/10.3389/fimmu.2018.02861 |
Ejemplares similares
-
Editorial: Immune Surveillance of the HIV Reservoir: Mechanisms, Therapeutic Targeting and New Avenues for HIV Cure
por: Prado, Julia G., et al.
Publicado: (2020) -
Targeting HIV-1 reservoirs in T cell subsets
por: Li, Min, et al.
Publicado: (2023) -
Targeting the Brain Reservoirs: Toward an HIV Cure
por: Marban, Céline, et al.
Publicado: (2016) -
Targeting NK Cells for HIV-1 Treatment and Reservoir Clearance
por: Duan, Siqin, et al.
Publicado: (2022) -
Immune mobilising T cell receptors redirect polyclonal CD8(+) T cells in chronic HIV infection to form immunological synapses
por: Wallace, Zoë, et al.
Publicado: (2022)