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Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease

INTRODUCTION: As the role of biomarkers is increasing in Alzheimer's disease (AD) clinical trials, it is critical to use a comprehensive temporal biomarker profile that reflects both baseline and longitudinal assessments to establish a more precise association between the change in biomarkers a...

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Detalles Bibliográficos
Autores principales: Wang, Guoqiao, Xiong, Chengjie, McDade, Eric M., Hassenstab, Jason, Aschenbrenner, Andrew J., Fagan, Anne M., Benzinger, Tammie L.S., Gordon, Brian A., Morris, John C., Li, Yan, Bateman, Randall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288312/
https://www.ncbi.nlm.nih.gov/pubmed/30569014
http://dx.doi.org/10.1016/j.trci.2018.10.009